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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0270c41a3f955f39d966c578f40fde69765ca98da0b52f5e01cd2799262c7e33' 
  AND token = '1bYePi7XoGgr+tRt9KRrGsn434WPuaUAaGjyoZA2pw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}