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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0240e4681d3106b1cbb7c66aa0a414777cbb695d70f41583822c04d6e87ec3a' 
  AND token = 'X8LR8n5Ff5GlQH++m8Kdqqv6FSgQI+X6IGSmHB9sTjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}