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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7821849452548209f4156bf86dfed30c1383c40c709febd87cf7417c0a18dc25' 
  AND token = 'wHew3/Vcgh+w7bI3F76uxbb8E7XNVdVO9SBeSKp0Ul8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}