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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761d10b61096894ae552abea936407f0cc18eea66b602060e442c6ffb2ee70b6' 
  AND token = 'VmxdECsrSzpPmz4cYd69BVOtpg5VmmL/DVjQEk6Xb8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}