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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc1d25687aa2cf8c76053164eb6b9fc299df9d875ee9a23aa3ae08216bc3ba1' 
  AND token = '5n1RQg64/yutDKgjV76TJlFfxLc7AVBmPMjPvuJW6a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}