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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e516b8b08460280ae10181ef750ea1fdeb25e211b06ddc1957d4f713d40439a' 
  AND token = 'W+2zBvFC1dnOT/azk2YQiyinrdVnqbbBLBSNES6I2rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}