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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4aa16b9610a16b9e422a4a9b531a79e870ddb8b2292dccc4b031a999f429ebd' 
  AND token = 'zRzvOKlMOK5PoG7do+XR9tuplCCwPNh8sylowJXY11I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}