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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62afc4331f771bac339838fbada0a3baee9e28b8a303eb09d4cc0eb9174cd643' 
  AND token = 'pIAr1IwqSMfXUuQOl/sQtRrIzSJkYMtoPOhfsmx4Kxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}