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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e780706fe86e069d03509398c87659b70d77b3268964d643d0218ef634dc1afb' 
  AND token = 'zie8bCI/4a7e++fNxcnC2eyvu4oaGWxKnySMC4Yu3zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}