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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cce326160a2bfbced6702b1d7263568dc64a755fc7346976cdf4a0f9d5184d' 
  AND token = 'h/IY4PiZO9OCGgZtkn1pF4xAWsWXr3yhjTb1OsyJKno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}