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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9a3c2b2be5bc43fcaf9d2edfbae58e67bb529fe2d0f43b383ac31507de1022' 
  AND token = '5DEcYW8ov24e4VVWy2sS7O+OcByO4/ecYKX0KCzMsZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}