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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456a097477e83e8ae3261cac1f42f30bd5022f5fa14af3c4664cecbab9594f84' 
  AND token = 'ysJ4CtP2i3XODanNAPg0LG+y9gU36/NNrmDRFL0oCtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}