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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c7d7b9e3161ac31d9929698c72744925b277f53318f617ec60f98e5e5f11dbd' 
  AND token = 'OIRFf8o3rM+XdHytO2n77mfihIGW9IbeGNNXSFO9uR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}