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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1343cecba6d150008865f4835bc15b6ab9e065692cbf9313c3acb72a17074a9' 
  AND token = 'iMY4RV/R2H/iTNw3hFahCH3rH6rBuCW3l8uuEV1uk1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}