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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbb75dece7992ca7d3e392cddb345adec2e51b59255f982662bd2f0e09964c44' 
  AND token = 'aSTG/X9HxVn8nIp4x3DlG4878L1T7a9goqSNKUZ/Gck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}