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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8512f1b6237be625b8a2dd3ef70215f49a0303d259ccaf7e3147036b165a6a53' 
  AND token = 'a4hFMzmtrk2BwyTr29MfRVYXj8eIqh76GMkkDL9mX+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}