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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4876ee416b0c990bce4f271b7d81629b6267a70ba0265e5749c8ee6da1ef756f' 
  AND token = 'dGkZRNw1p61vRpEZbLuIVUgjRuHhX0WbVrRLU35kVWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}