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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8508c2e7e3d0462f61e027710c2f516f201935e750b602ff1ac713b9512cb25' 
  AND token = 'l+zzklripr4xcd8Do/m+eFmwotKax8Khwp/fo1/KIvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}