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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a56aaab18e18138186e3e7811e4fb43c6125e97de19cb42f763a9e86f6c344' 
  AND token = 'tguLEOpQm7K95kbrU96m+3pDHkL85w4kIKgEWJEgjJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}