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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc621cec6079706367809053d0d5fd54ec9f13ce7e85bdf8d44a7d646dd46b5' 
  AND token = 'CANIn+7G0i3GDtZaRR7eTxl57G4i/JBK/QdBB1z+v5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}