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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d674b8ac7af0a3d5a0c188f5824da03688f0f858bb0d57c04e208bbaa0f8c7c' 
  AND token = 'r1Dj24dvewuB6wDwbp6BjyLKRjtef6/r6QDrrsjw0Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}