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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e063a56f604f61d3198baf758ca369c765a7f8f055da134dc4104240b5f0b4' 
  AND token = '/pAUzt4OCEXMPDnNhmho21ZviIG4VdD0hKIRu/U6cuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}