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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a997f69a911467412414c45f11441ef06bbd8f3e6c5f2115fb48443026a047f' 
  AND token = 'Vgwi4906ULilFsY+CnGteIABw7OEsCboXFlRVi4cvsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}