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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c60b432e812263bc1347d56c5b03bd6bf0ff1773ed47ce4d016e80ccaaa9c66' 
  AND token = 'Aa0G11B/Eel56AyqyYh/EbJtN545Geu/6DrVqRcWBLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}