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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e8f366d7dba7ca46aa1e88dc14ccb60e177280c55ff5ef28d9a2c21cacacdf' 
  AND token = 'EZgp57sCHASMYcumvOCivJLB7aQ/Dt8MRxQQcWMD8i0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}