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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6d5df4d2add135867f6be9c06499d70e78f2491c761803c0b03fc75348bcd03' 
  AND token = 'OnStvEY/XKFXlZMEFS1UnHYleWMMggWrQKn9Am8dnl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}