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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2240ca2a359c1a8a624e4744f60cc573dbe67289f2c2b9fe02cb28aecbe60931' 
  AND token = '4YKLcI1XgoSXFjoLMDqLVp+zOJHJX8N29MmjaBNCXdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}