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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b94c78471cba02c0e9ef0ba425faf159749b6152fb39f415c2b5e727bb406af1' 
  AND token = 'I2GFosWxZ73rpQQr25ur6Be30HRigVJyBiwQN2v2dzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}