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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bffcd0b8f1f6714bb14b5ec2b79dcc693bbac890bb480ea0307dccde33e5378' 
  AND token = '7ALPza8tHt4Q117Geng45aAP02yXUQxHjjKv5KBZ1vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}