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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3dfd2d4cb82d428d4d782dd366077fc75c0ae16907e9294b900130b4e31ea5' 
  AND token = 't6yI9WFjfUkbYyG+0V81PfzYWoGb6ijsCPqCl1yk3ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}