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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8004ce775a81e9de945dab562f4bfc8f9e2540e59fa4fc0788eaf6bd82dfd65' 
  AND token = '2nZpHQCXPwjCs2MDKsKw/EMqyibAXsn4Fs6ixSFYYQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}