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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505abe81eb33e5784f913413306714ce1912db0c321b1c662077f24f27138938' 
  AND token = 'Dy3I8rqXLxaud3fPAsLi3y7B/gWnbYt4mpq7SD58NhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}