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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6e6676d416076705be1921d93dd5c51436141506f44f5cba2c4a41d6339e995' 
  AND token = 'RS+8D4n8hEjiNqq7TrAebU+Ca7GoVoHxvrsv1DbZdCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}