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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d6cabb7c15b23bc2db964d89ed74a5efeaf566cb3437adff1d58bfae10cca5' 
  AND token = 'lH9XASG6kIeTWTltS6Hacz14G9ZWFyoon7l0iyk8Kr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}