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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd3c1fe90e5f8c51511325339d59066b9a87863dbe4971c99bcc7a4b754008c6' 
  AND token = 'IYsyeWT2qlrrR68yGMX3m0mVJLEJloOoO/CWIhtayUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}