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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f25cd7454d01b6da35ec03609cf49afa7dc013fdbd74a4e284208fbd85c5fba' 
  AND token = 'OS82AkpxjDNuW6VlN0yEkWMBTBDFwdlq+2paKQbY/28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}