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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc6c30c73807f1c5c197639b75cff5adcadf7a3fe881ec400610a312b318bb1' 
  AND token = 'g2rCwa2VQEdiIPqUeIpaa9s1wcmY6d66C+xQ/Go7B+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}