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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '803cf395f224febbed12bf9ada5e9430b33b93560d4376265722d670ef247256' 
  AND token = 'iC3Tgkra0OUnHHZZUSD3qzN3Uqx6ql/ykOV6j54LNqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}