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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '012b9733732a05b0675baa596e1028f7dd02e2de149d737a5be7c026dda8f5a0' 
  AND token = 'GRVWA+jppEz3aWM/P/ok6Y9xEAc1wu6ccs2t6HbKLBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}