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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2870ac5839d2d002a018178e93692d0d87ebcda2c9edbce85d252d6e189a4dfc' 
  AND token = 'JBtPzKDXEpqvJzPHRVW65hj9hdWLH2XM2Tg29Z+s8bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}