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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150ee38cdbc427fb1555ca08f18c8996a5df863c91b5b5e41fa718e8176c8641' 
  AND token = 'Wz/X/zF8TfTCOzFaFoTHWEvL3ea1rYamvCNon6EvE7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}