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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45035a1b71d087b4192c1b2516b96a5e4c00c7c90ef588df65292a292d68605f' 
  AND token = '73xMys9oLn6ZMSeAhzBF9jiMiFBkfRlJt2qBEsIJgaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}