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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e497e7a9b7b084690b92efceec3e49d121881b91346ecf5e9337f5afe2c84a0' 
  AND token = 'Hm/+5ii1tAQGGipOfshGQIEhtdcK4Ox/MZ+wq6mX+58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}