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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b4e3f3153e65aa787022f06494e1cc5b8d7e2c58f023d2148ba7ec4d4cf824' 
  AND token = '/GePrVmALA3zj1hjDlp+t3Rpmw6lDh3eP0+Xy/63u7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}