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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9748eb8b4df61cdad6015999512d9051657e6bf7dd6af521fb4a2454ddde5a59' 
  AND token = 'SIX+WLhWtdIGAtkyhcb35o4VA/s/KYy7xBJe8bWHnas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}