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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95fa8c94999807e686489422a1d18b736b16a2538f86386be93f75dc192d05e6' 
  AND token = 'pYE8PTxnv0ACAC9H3IQ/nimW5nCQtre3mTdPt0Ffixw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}