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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8167a43bfb66f234481f6ae150ba01ad8a67d35c0c8e04e1051af444d0f2e057' 
  AND token = 'z7apwYIgTnQG2k9DTjvDZ0MxUwOB6S3RqjqaDa2CFSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}