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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e045ece4af2b440c4de782ae7fc44827c049b573dfeae2884655d48ac5de9bc1' 
  AND token = 'dR9LpXbwM5ZVpLtjW4URyoupOLCoZPm2D3WQSbTDF2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}