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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e67e95f9895111264ace1bbe0d5f134db9eb1dfd2f03512abe658163da4ff7' 
  AND token = 'oq4V2BE6UPLHTcYa4etXbeqjS59dbM4F6vmLFGLB/2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}