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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811e54d5d6b7cc04c7639a12b7f04166f1dfb428d0101fd781441e46c4c23e36' 
  AND token = 'fWH8VBt1W6s0Y6Hb/upXOyCDC2DzAlnxZD877wgdbfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}